Scientific Laboratory of Medical and Biological Informatics

Laboratory Head

Kafedra mudiri

Adilova Fatima Tuychievna

Laboratory Head

πŸ“§ Email: fatadilova@gmail.com

πŸ“ž Telefon: +99897 3946419

πŸ•” Reception days:

🏒 Office number: 305

πŸ“ Address:

Address: 100174, Tashkent city, Almazar district, University street, house 4

More details

About Laboratory

The Medical Cybernetics Laboratory was established in 1969 at the Institute of Cybernetics of the Academy of Sciences of Uzbekistan and was headed until 1980 by Doctor of Technical Sciences, Professor Khusan Qodirovich Qodirov. Then the laboratory was taken over by Doctor of Technical Sciences, Professor Fotima Tuychievna Adilova, who continues to lead it to the present day. The laboratory has worked on solving computer diagnostics problems, modeling and predicting the outcomes of diseases in various fields of medicine. It has been using pattern recognition methods and mathematical modeling techniques. The laboratory has worked closely with specialized scientific centers and clinics of Uzbekistan and other republics.

The Medical Biological Informatics Laboratory has been conducting its scientific activities as part of the Institute of Mathematics from 2007 to the present day.

Scientific research has been carried out on the basis of numerous foreign grants. In particular, work was performed under 5 NATO grants totaling 730,000 US dollars, a European Union grant worth 15,000 euros, and Switzerland's SCOPES scientific fund grant amounting to 26,500 US dollars.

Through the initiative of F.T. Adilova, approximately 800,000 US dollars in total have been obtained from international funds and spent on acquiring laboratory equipment and conducting scientific research.

The laboratory has identified new patterns in disease development and developed computer diagnostics technologies and treatment optimization in various fields of medicine, which have been implemented in clinics of the Ministry of Health of Uzbekistan. These include telemedicine systems in hospitals in Tashkent, Qarshi, and Nukus cities, in two military hospitals of the Ministry of Defense of the Republic of Uzbekistan (Tashkent, Fergana), and diagnostic and treatment programs for various disease profiles. The effectiveness of implementation consists in improving the quality of medical care for the population.

Additionally, projects have been completed on the topics "Mathematical modeling of molecular interactions through the application of computer methods for multiparametric analysis of data in a Grid environment," "Development of computer applications for creating new medicines," and "Development of virtual methods of molecular optimization in the development of new drugs." Since April 2020, a project is being implemented to develop a disease assessment system for patients with COVID-19 for the Republican Scientific Center of Emergency Medical Care.

In 2020, by presidential decree, F.T. Adilova was awarded the "Mehnat Shuhrati" (Labor Glory) Order.

Laboratory Staff

Adilova Fatima Tuychievna

Tibbiy-biologik informatika ilmiy laboratoriyasi mudiri More details β†’

Davronov Rifqat Rahimovich

Katta ilmiy xodim More details β†’

Ikramov Alisher Akramovich

Katta ilmiy xodim More details β†’

Kushmuratov Samariddin Ibodulla o’g’li

Kichik ilmiy xodim More details β†’

Misirov Farxod Abdulla o’g’li

Kichik ilmiy xodim More details β†’

Safarov Ro’zmat Abdiqayum o’g’li

Kichik ilmiy xodim More details β†’

Scientific Activity

 

Currently, the laboratory is conducting research in the following directions:

Generative artificial intelligence and quantum technologies. Generative artificial intelligence (AI), "deep technologies," and APIs have been prominent technological trends in recent years. In June 2024, the UN declared 2025 as the International Year of Quantum Science and Technology. Quantum technologies are transforming industrial sectors using the principles of quantum mechanics. Quantum computers can model molecular interactions at unprecedented speeds, which accelerates the development of new drugs, implements personalized medicine, and takes disease diagnostics to a qualitatively new level. Research conducted in this direction focuses on Kolmogorov-Arnold neural networks, cardiovascular disease prediction on multi-ethnic data benchmarks, quantum algorithms, quantum machine learning (QML), and quantum-enhanced image processing. The results not only enrich theoretical AI understanding but also serve as an important tool in the development of modern medicine and technology.

Cluster analysis and intelligent data modeling. Cluster analysis is one of the fundamental tasks in the field of intelligent modeling and data analysis. In this direction, methods of analyzing graph density variation, detecting clusters with complex nonlinear shapes, identifying dense "cores," and reconstructing the complete structure of clusters are studied. The main goal of the research is to develop a new cluster validation index (Core Separation Index, CSI), create its theoretical foundations, and prove its effectiveness through experimental comparison with other well-known indices. These methods reduce the need for manual hyperparameter selection and increase the level of automation in data analysis.

Efficient fine-tuning of large language models. This direction studies Parameter-Efficient Fine-Tuning (PEFT) methods to address the computational and memory cost problems arising from the growing size of large language models. Research is focused on developing and testing a new hybrid method, OLoRA+, which combines the structured initialization of OLoRA with the accelerated optimization of LoRA+. The main goal is to adapt pre-trained models by selectively fine-tuning a small number of additional parameters while keeping most of the original model frozen, and to reveal new dynamics associated with the selection of learning rate ratios. The results enable efficient and economically cost-effective tuning of AI models.

Vehicle detection and road traffic safety. This direction is dedicated to creating Vehicle Make and Model Recognition (VMMR) systems to ensure road traffic safety. Research involves developing a practical system that detects vehicle models and body colors in real CCTV streams, taking into account local conditions (road surface condition, camera placement, lighting practices). Models adapted to the transportation environment conditions of Uzbekistan, which are not adequately represented in open datasets, are being created. These results enable improvement of traffic management, automated monitoring, and security systems.

Statistical analysis in clinical research. This direction studies problems of identifying statistically significant clinical-laboratory and instrumental indicators associated with mortality in patients suffering from diseases such as arterial hypertension and diabetes mellitus, with the aim of applying scientific research results to clinical practice. Research is based on retrospective data and covers long-term follow-up periods (up to 8 years). The main goal is to create reliable statistical models for prediction across various healthcare problems and to assist medical personnel in making clinical decisions.

International Cooperation

The laboratory actively collaborates scientifically with many institutes and universities, including:

  • Moscow and Novosibirsk State Universities;

  • Kazan (Volga Region) Federal University;

  • The Universities of Stanford, North Carolina, North Dakota, Cincinnati (USA);

  • Helmholtz Zentrum München (Germany).

Seminars

Application of Artificial Intelligence in Medicine and Chemistry (scientific seminar)

Seminar venue: ZOOM ID- 71367387143

The seminar is held every Wednesday at 10:00

Seminar leader: F.T. Adilova, Doctor of Technical Sciences, Professor, Laboratory Director, Seminar secretary: R.R. Davronov, Senior Research Fellow